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Hepatic Encephalopathy

Hepatic encephalopathy ( HE) is caused by chronic and acute liver diseases or portal systemic shunting. Hepatic encephalopathy is a kind of psychological problem based on metabolic disorder. The clinical manifestations of Hepatic encephalopathy are slight problem which can only be discovered by intelligence test or electrophysiology, behavior disorder, conscious disturbance and even hepatic coma. The slight hepatic encephalopathy is also called subclinical hepatic encephalopathy (SHE) or minimal hepatic encephalopathy (MHE).

The main cause of hepatic encephalopathy is central nervous impairment. Acute and chronic liver dysfunction so that toxic substances from the gut to the liver detoxification or can not be cleaned, or to bypass the liver via collateral circulation directly into the systemic circulation. Toxic substances through the blood-brain barrier to reach the brain, causing brain dysfunction. The primal pathogenies are chronic and acute liver function disorder and brain disorder. Usually, hepatic encephalopathy is based on chronic and acute hepatic failure, liver cirrhosis, primary hepatic carcinoma, acute fatty liver of pregnancy( AFLP) and severe biliary tract infection.

Severe hepatic encephalopathy may be life-threatening. because repeated episodes, prognosis is poor. degree of hepatic coma, the worse the prognosis,the higher the mortality. The following are some attentions:

1.Identify causes of hepatic encephalopathy and treat accordingly.Hepatic encephalopathy have various causes. Actively find the cause and promptly removed, can effectively stop the development of hepatic encephalopathy. As an active infection control, correct water and electrolyte imbalance, eliminate constipation, limiting protein diet, improve kidney function and other measures will help control the development of hepatic encephalopathy.

2.Nutritional support. Patients with hepatic encephalopathy feel inappetence, some even in comatose stage and cannot take food. Therefore, nutritional support appears very vital. In the first several days, patients should avoid taking protein, and take less fat because fat can delay the gastric emptying. Supplying patients with enough heat (1200-1600Kcal, mainly in the form of carbohydrate) is necessary. Besides, patients should supplement various vitamins (such as vitamin B, C and K.) and proper blood plasma to help recover liver cells.

In daily life, patients with hepatic encephalopathy should avoid taking food high in protein.Observe whether patients with personality and behavioral abnormalities, so early detection and early treatment.

3.Decrease the formation and absorption of hydrogen nitride and other harmful substances in intestinal tract. When patients have symptom of encephaledema, they should receive dehydration treatment. Besides, balancing water electrolyte and acid-base, keeping the airway open, controlling endotoxemia, preventing gastrointestinal bleeding, kidney failure and heart failure are still of great importance.

4.Liver transplant. For patients with recurrent hepatic encephalopathy caused by liver cirrhosis and chronic hepatic failure, liver transplant might be the only effective treatment way.

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Woman
I was infected with hepatitis C and then it developed to liver cirrhosis.I started to take YHK in 2006, after one week, my ALT and AST values began to decrease. In Dec, I stopped the injection treatment.YHK help me a lot..
Men
I’m a liver cirrhosis patient. I was ho